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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | W | L | Pct | ERA | G | GS | CG | SHO | SV | IP | H | ER | HR | BB | SO |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Carlos Zambrano | 2001-2019 | 16 | 12 | .571 | 3.50 | 76 | 25 | 0 | 0 | 10 | 224.0 | 202 | 87 | 15 | 72 | 178 |
| Victor Zambrano | 2002-2003 | 5 | 0 | 1.000 | 2.08 | 37 | 0 | 0 | 0 | 1 | 39.0 | 31 | 9 | 0 | 21 | 46 |
| Félix Zamora | 2008-2022 | 41 | 24 | .631 | 2.62 | 123 | 72 | 4 | 1 | 14 | 580.2 | 462 | 169 | 36 | 180 | 562 |
| Raúl Zamora | 2025-2031 | 53 | 38 | .582 | 3.45 | 120 | 114 | 9 | 4 | 0 | 760.0 | 673 | 291 | 61 | 240 | 663 |
| Vincente Zamora | 2024-2028 | 23 | 20 | .535 | 4.70 | 62 | 56 | 5 | 1 | 2 | 342.2 | 312 | 179 | 46 | 137 | 329 |
| Carlos Zaragoza | 2012-2023 | 15 | 6 | .714 | 2.54 | 81 | 29 | 1 | 1 | 2 | 262.2 | 213 | 74 | 12 | 67 | 171 |
| José Zarate | 2025-2031 | 8 | 14 | .364 | 5.07 | 64 | 33 | 1 | 1 | 0 | 252.0 | 259 | 142 | 48 | 111 | 285 |
| Robert Zavala | 2030-2031 | 2 | 29 | .065 | 6.90 | 69 | 33 | 0 | 0 | 1 | 214.0 | 279 | 164 | 39 | 126 | 136 |
| Malcolm Zegwaard | 2012-2022 | 24 | 17 | .585 | 3.53 | 91 | 59 | 0 | 0 | 8 | 370.0 | 280 | 145 | 23 | 215 | 372 |
| Jonathan Zeller | 2027-2028 | 6 | 5 | .545 | 3.97 | 52 | 3 | 0 | 0 | 14 | 88.1 | 82 | 39 | 11 | 30 | 59 |
| Tommy Zellers | 2021-2028 | 31 | 28 | .525 | 3.77 | 80 | 80 | 4 | 1 | 0 | 496.0 | 492 | 208 | 47 | 126 | 297 |
| Xiao-shuang Zhou | 2031-2031 | 8 | 11 | .421 | 4.68 | 23 | 23 | 0 | 0 | 0 | 136.2 | 139 | 71 | 20 | 36 | 86 |
| Brad Ziegler | 2011-2020 | 15 | 12 | .556 | 3.93 | 93 | 17 | 0 | 0 | 12 | 219.2 | 193 | 96 | 11 | 94 | 134 |
| Craig Zimmerman | 2021-2031 | 30 | 37 | .448 | 4.46 | 135 | 78 | 3 | 0 | 24 | 551.1 | 586 | 273 | 80 | 164 | 321 |
| Ron Zimmerman | 2019-2024 | 36 | 41 | .468 | 4.38 | 120 | 115 | 3 | 1 | 1 | 709.0 | 657 | 345 | 113 | 260 | 618 |
| Jordan Zimmermann | 2014-2018 | 4 | 2 | .667 | 3.14 | 15 | 8 | 0 | 0 | 2 | 63.0 | 53 | 22 | 10 | 9 | 57 |
| Barry Zito | 2004-2015 | 35 | 30 | .538 | 3.66 | 102 | 84 | 6 | 1 | 1 | 587.1 | 568 | 239 | 66 | 170 | 491 |
| Peter Zoccolillo | 2007-2011 | 0 | 0 | .000 | 2.79 | 3 | 0 | 0 | 0 | 0 | 9.2 | 13 | 3 | 0 | 4 | 0 |
| Joel Zumaya | 2010-2023 | 14 | 6 | .700 | 2.70 | 53 | 39 | 0 | 0 | 6 | 233.2 | 150 | 70 | 11 | 121 | 289 |
| Jesús Zúñiga | 2026-2028 | 7 | 11 | .389 | 4.03 | 27 | 27 | 0 | 0 | 0 | 145.1 | 142 | 65 | 13 | 61 | 143 |
| Jorge Zúñiga | 2030-2031 | 2 | 4 | .333 | 4.33 | 21 | 9 | 0 | 0 | 0 | 68.2 | 60 | 33 | 7 | 39 | 60 |
| Miguel Zúñiga | 2026-2030 | 46 | 36 | .561 | 3.87 | 110 | 110 | 6 | 1 | 0 | 693.2 | 684 | 298 | 53 | 181 | 410 |
