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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Duane Moody | 272.0 | 2013 | |
| 2 | Phil Barnes | 260.0 | 2013 | |
| 2 | Dan Evans | 260.0 | 2010 | |
| 4 | Brian Tollberg | 255.0 | 2011 | |
| 5 | Henry Olson | 247.0 | 2011 | |
| 6 | Freddy Garcia | 239.0 | 2010 | |
| 7 | Jesús Santiago | 235.0 | 2011 | |
| 8 | Logan Kensing | 233.0 | 2015 | |
| 9 | Elvis Lambert | 227.0 | 2014 | |
| 9 | Dave Ferneyhough | 227.0 | 2003 | |
| 9 | Will Davidson | 227.0 | 2009 | |
| 12 | Kyle Snyder | 223.0 | 2004 | |
| 13 | Chuck Smith | 221.0 | 2012 | |
| 14 | Jerome Williams | 220.0 | 2011 | |
| 14 | Keith Compton | 220.0 | 2010 | |
| 16 | Doug Ball | 219.0 | 2013 | |
| 16 | Kevin Chamberlain | 219.0 | 2007 | |
| 18 | Nick Fisher | 218.0 | 2013 | |
| 19 | Steve Jarvis | 217.0 | 2012 | |
| 19 | Kevin Chamberlain | 217.0 | 2002 | |
| 21 | David Bush | 215.0 | 2010 | |
| 21 | Jesse Foppert | 215.0 | 2012 | |
| 23 | Ryan Rupe | 213.0 | 2004 | |
| 23 | César Camilleris | 213.0 | 2010 | |
| 25 | Armando Galarraga | 212.0 | 2015 | |
| 25 | Henry Deveau | 212.0 | 2007 | |
| 25 | Lee Gentry | 212.0 | 2002 | |
| 28 | Geoffrey Edwards | 211.0 | 2017 | |
| 28 | Kyle Lohse | 211.0 | 2013 | |
| 28 | Kyle Dawson | 211.0 | 2016 | |
| 28 | Jeremy Guthrie | 211.0 | 2010 | |
| 28 | Jasper Phillips | 211.0 | 2018 | |
| 33 | Eduardo Ruíz | 210.0 | 2016 | |
| 33 | Steve White | 210.0 | 2016 | |
| 35 | Ryan Jensen | 209.0 | 2007 | |
| 36 | Earl Collins | 208.0 | 2012 | |
| 37 | Terry Coleman | 207.0 | 2011 | |
| 37 | Cody Wade | 207.0 | 2011 | |
| 37 | Ryan Bowen | 207.0 | 1991 | |
| 40 | Shawn Sedlacek | 206.0 | 2012 | |
| 40 | Brandon Lyon | 206.0 | 2004 | |
| 40 | David Bush | 206.0 | 2005 | |
| 43 | Félix Zamora | 205.0 | 2009 | |
| 43 | Veríssimo Hervedeiro | 205.0 | 2006 | |
| 43 | Kyle Lohse | 205.0 | 2014 | |
| 43 | John Roper | 205.0 | 2002 | |
| 43 | Stephen Strasburg | 205.0 | 2011 | |
| 48 | Chuck Smith | 204.0 | 2012 | |
| 48 | Jimmy Thornton | 204.0 | 2014 | |
| 48 | Jair Jurrjens | 204.0 | 2013 | |
| 48 | Justin Masterson | 204.0 | 2011 | |
| 48 | Phil Barnes | 204.0 | 2014 | |
| 48 | Andrés Silva | 204.0 | 2017 | |
| 48 | Curt Cameron | 204.0 | 2004 | |
| 55 | John Roper | 203.0 | 2006 | |
| 55 | Carlos Cotter | 203.0 | 2007 | |
| 57 | Denny Keys | 202.0 | 2016 | |
| 57 | Riccardo Aalbers# | 202.0 | 2031 | |
| 57 | Juan Vega | 202.0 | 2014 | |
| 57 | Roberto Leal | 202.0 | 2015 | |
| 57 | Brandon Lyon | 202.0 | 2006 | |
| 57 | Richard Verhoeve# | 202.0 | 2025 | |
| 63 | Edgar Stevenson | 201.0 | 2003 | |
| 63 | Jake Young | 201.0 | 2013 | |
| 63 | Kevin Chamberlain | 201.0 | 2006 | |
| 66 | Josh Fogg | 200.0 | 2011 | |
| 66 | Matt Garza | 200.0 | 2010 | |
| 66 | Duane Moody | 200.0 | 2012 | |
| 66 | Scott Downs | 200.0 | 2000 | |
| 66 | Jorge Cortés | 200.0 | 2012 | |
| 71 | Jerry Burrell# | 199.0 | 2017 | |
| 71 | Julio Teheran | 199.0 | 2015 | |
| 71 | Roland Gates | 199.0 | 2014 | |
| 71 | Rich Bygrove | 199.0 | 2002 | |
| 71 | Damon Lane | 199.0 | 2010 | |
| 71 | Javier Bellini# | 199.0 | 2022 | |
| 71 | Byron Guffin | 199.0 | 2011 | |
| 71 | Flynn Garrett | 199.0 | 2017 | |
| 79 | Ricky Nolasco | 198.0 | 2011 | |
| 79 | Jeremy Lynn | 198.0 | 2006 | |
| 79 | Glen Casey | 198.0 | 2011 | |
| 79 | Stan Spencer | 198.0 | 1998 | |
| 83 | Malcolm Zegwaard | 197.0 | 2012 | |
| 83 | Daniel Johnston# | 197.0 | 2025 | |
| 83 | Eric Pollock | 197.0 | 2005 | |
| 83 | Rick Hartman# | 197.0 | 2020 | |
| 83 | Scott Downs | 197.0 | 2011 | |
| 83 | John Roper | 197.0 | 2007 | |
| 89 | Bob Martin | 196.0 | 2016 | |
| 89 | Esteban Martínez | 196.0 | 2003 | |
| 89 | John Garland | 196.0 | 2017 | |
| 89 | Barry Zito | 196.0 | 2012 | |
| 89 | Rich Saunders | 196.0 | 2003 | |
| 89 | Steve Hayes | 196.0 | 2017 | |
| 89 | Mike Campbell | 196.0 | 2010 | |
| 89 | David Bryant | 196.0 | 2003 | |
| 89 | Archie Anderson | 196.0 | 2013 | |
| 89 | Robert Dixon# | 196.0 | 2030 | |
| 89 | Ramiro Mendoza | 196.0 | 2003 | |
| 100 | Mario Cruz | 195.0 | 2017 |
