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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | W | L | Pct | ERA | G | GS | CG | SHO | SV | IP | H | ER | HR | BB | SO |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Carlos Zambrano | 2001-2019 | 163 | 93 | .637 | 3.38 | 632 | 375 | 2 | 2 | 14 | 2327.2 | 2119 | 874 | 146 | 959 | 2060 |
| Victor Zambrano | 2001-2013 | 48 | 41 | .539 | 4.20 | 662 | 0 | 0 | 0 | 74 | 693.2 | 683 | 324 | 71 | 347 | 515 |
| Félix Zamora | 2010-2021 | 101 | 103 | .495 | 4.35 | 364 | 275 | 17 | 9 | 1 | 1837.0 | 1934 | 888 | 246 | 495 | 1415 |
| Raúl Zamora | 2026-2030 | 13 | 26 | .333 | 5.43 | 46 | 46 | 1 | 0 | 0 | 281.2 | 323 | 170 | 41 | 98 | 210 |
| Vincente Zamora | 2025-2028 | 8 | 7 | .533 | 4.69 | 80 | 8 | 0 | 0 | 3 | 149.2 | 143 | 78 | 21 | 65 | 156 |
| Carlos Zaragoza | 2013-2022 | 36 | 46 | .439 | 4.75 | 453 | 43 | 0 | 0 | 36 | 821.2 | 935 | 434 | 59 | 304 | 551 |
| José Zarate | 2025-2030 | 41 | 47 | .466 | 5.50 | 120 | 106 | 5 | 0 | 0 | 680.1 | 811 | 416 | 128 | 240 | 621 |
| Malcolm Zegwaard | 2013-2020 | 66 | 57 | .537 | 4.41 | 294 | 130 | 1 | 1 | 4 | 926.2 | 825 | 454 | 66 | 562 | 764 |
| Tommy Zellers | 2023-2028 | 31 | 43 | .419 | 4.94 | 234 | 66 | 1 | 0 | 19 | 597.1 | 636 | 328 | 59 | 227 | 347 |
| Brad Ziegler | 2013-2021 | 39 | 62 | .386 | 5.44 | 402 | 59 | 0 | 0 | 55 | 735.2 | 861 | 445 | 53 | 341 | 380 |
| Craig Zimmerman | 2023-2030 | 42 | 56 | .429 | 4.68 | 260 | 114 | 3 | 0 | 12 | 884.1 | 918 | 460 | 115 | 382 | 537 |
| Ron Zimmerman | 2021-2023 | 7 | 10 | .412 | 7.25 | 32 | 21 | 1 | 1 | 2 | 126.2 | 172 | 102 | 27 | 57 | 100 |
| Jordan Zimmermann | 2014-2024 | 60 | 65 | .480 | 5.02 | 495 | 120 | 3 | 1 | 9 | 1213.0 | 1358 | 677 | 204 | 280 | 779 |
| Barry Zito | 2000-2014 | 126 | 136 | .481 | 4.30 | 387 | 346 | 27 | 7 | 1 | 2280.1 | 2159 | 1089 | 294 | 862 | 1814 |
| Joel Zumaya | 2011-2023 | 55 | 50 | .524 | 4.07 | 634 | 49 | 0 | 0 | 147 | 878.2 | 781 | 397 | 75 | 468 | 966 |
| Jesús Zúñiga | 2024-2028 | 10 | 15 | .400 | 4.75 | 136 | 14 | 0 | 0 | 2 | 265.1 | 256 | 140 | 42 | 123 | 297 |
| Jorge Zúñiga | 2031-2031 | 3 | 3 | .500 | 5.54 | 38 | 0 | 0 | 0 | 3 | 39.0 | 39 | 24 | 4 | 23 | 33 |
| Miguel Zúñiga | 2028-2029 | 8 | 4 | .667 | 5.34 | 15 | 15 | 0 | 0 | 0 | 92.2 | 94 | 55 | 7 | 28 | 47 |
