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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Jose Valentin* | 420 | 1992-2009 | |
| 2 | Juan Rocha# | 345 | 2011-2031 | |
| 3 | Ian Desmond | 275 | 2013-2025 | |
| 4 | Ryan Zimmerman* | 273 | 2008-2018 | |
| 5 | Vern Carpenter | 263 | 2002-2015 | |
| 6 | Nomar Garciaparra | 261 | 1996-2010 | |
| 7 | José Díaz# | 256 | 2021-2031 | |
| 8 | Millard Lynch# | 255 | 2018-2031 | |
| 8 | Bob Stoltzfus# | 255 | 2016-2031 | |
| 10 | Ray Beatty | 245 | 2000-2012 | |
| 11 | Dale Stevenson# | 236 | 2015-2031 | |
| 12 | José Rodríguez | 213 | 2011-2024 | |
| 13 | Terence Brown# | 205 | 2017-2031 | |
| 14 | Santiago González# | 192 | 2024-2031 | |
| 15 | Willie Greene | 191 | 1992-2002 | |
| 16 | Tony Batista | 190 | 1996-2009 | |
| 17 | Bill Hall | 186 | 2002-2012 | |
| 18 | Francisco Lindor# | 184 | 2021-2031 | |
| 19 | William Crosby | 173 | 2005-2015 | |
| 20 | Tom Perkins | 172 | 2006-2023 | |
| 21 | Carlos Correa# | 168 | 2023-2031 | |
| 22 | Travis Fryman | 165 | 1990-2005 | |
| 23 | Luis Pérez | 163 | 2012-2018 | |
| 24 | Mark Knight | 149 | 2017-2030 | |
| 25 | Thom Horton | 145 | 2015-2028 | |
| 26 | Chase Cobb | 143 | 2004-2013 | |
| 27 | Bob Lowery | 126 | 2001-2011 | |
| 28 | Troy Tulowitzki | 121 | 2009-2015 | |
| 29 | Michael Eddison | 119 | 2007-2018 | |
| 29 | Marvin Nixon | 119 | 2013-2025 | |
| 31 | Tony Torres# | 118 | 2025-2031 | |
| 32 | Donald Osting | 116 | 2009-2016 | |
| 33 | Fernando Tatis Jr.# | 114 | 2024-2031 | |
| 34 | Geronimo Pena | 112 | 1990-2002 | |
| 34 | Bryan Yates | 112 | 2013-2022 | |
| 36 | Rich Aurilia | 111 | 1995-2009 | |
| 37 | Jose Hernandez | 110 | 1992-2002 | |
| 38 | Darryl Hamilton | 109 | 2017-2023 | |
| 38 | Tony Rodriguez | 109 | 1996-2007 | |
| 40 | Alex Gonzalez | 103 | 1998-2005 | |
| 41 | Peter Donaldson# | 102 | 2015-2031 | |
| 41 | John Smith | 102 | 2003-2015 | |
| 43 | Vinny Castilla | 96 | 1994-2005 | |
| 43 | Omar Infante | 96 | 2002-2016 | |
| 43 | Don Palmer | 96 | 2010-2028 | |
| 46 | Adam Brown# | 95 | 2019-2031 | |
| 46 | José Durán | 95 | 2007-2015 | |
| 48 | Stephen Drew | 92 | 2010-2015 | |
| 49 | Austin Martin# | 91 | 2026-2031 | |
| 50 | Cal Beason | 90 | 2017-2027 | |
| 51 | Kyle Seager | 86 | 2009-2023 | |
| 52 | Ernest Eaton# | 85 | 2019-2031 | |
| 52 | Edgar Renteria | 85 | 1996-2010 | |
| 54 | Paco Allegue | 83 | 2000-2010 | |
| 55 | Jimmy Rollins | 80 | 2000-2007 | |
| 56 | Dave Gallagher# | 79 | 2020-2031 | |
| 57 | Alex Rodriguez | 78 | 1995-2004 | |
| 58 | Allen Campbell# | 77 | 2025-2031 | |
| 58 | Derek Jeter | 77 | 1995-2010 | |
| 60 | Manny Machado | 76 | 2015-2020 | |
| 60 | Bill Selby | 76 | 1996-2003 | |
| 60 | Larry Wagner# | 76 | 2021-2029 | |
| 63 | Felipe Lopez | 75 | 2001-2012 | |
| 64 | Henry Stevens# | 73 | 2024-2031 | |
| 65 | David Esquivel | 72 | 2004-2009 | |
| 66 | Mark DeRosa | 71 | 1999-2006 | |
| 66 | William Haines# | 71 | 2024-2031 | |
| 68 | Alfredo Espinoza | 70 | 2005-2013 | |
| 69 | Lane Bailey# | 68 | 2023-2031 | |
| 70 | Alex S Gonzalez | 65 | 1994-2003 | |
| 71 | Vaughan O'Durhan | 64 | 2014-2025 | |
| 72 | Alex Bregman# | 63 | 2022-2031 | |
| 73 | Rafael Furcal | 62 | 2000-2009 | |
| 74 | Jose Offerman | 61 | 1990-2002 | |
| 74 | Dean Palmer | 61 | 1991-2000 | |
| 76 | Bob Anderson | 60 | 2018-2027 | |
| 77 | Pedro Ramírez# | 59 | 2022-2031 | |
| 78 | Jason Graham | 58 | 2007-2018 | |
| 78 | Mike Johnstone | 58 | 2009-2016 | |
| 80 | Geoff Blum | 55 | 1999-2014 | |
| 81 | Kurt Abbott | 54 | 1993-2003 | |
| 82 | Chipper Jones | 53 | 1993-2005 | |
| 83 | Manuel Barajas | 52 | 2016-2022 | |
| 83 | Jose Castillo | 52 | 2005-2014 | |
| 83 | Jorge Velandia | 52 | 1999-2010 | |
| 86 | John Smith# | 51 | 2016-2030 | |
| 87 | Keith A Miller | 50 | 1987-2004 | |
| 87 | Gary Rice | 50 | 2011-2019 | |
| 89 | Shane Andrews | 49 | 1995-2002 | |
| 89 | Prakoso Prawiranega* | 49 | 2007-2024 | |
| 91 | Britt Bryant | 48 | 2021-2028 | |
| 91 | Starlin Castro | 48 | 2016-2027 | |
| 93 | Orlando Cabrera | 47 | 1997-2008 | |
| 93 | Mark Grudzielanek | 47 | 1995-2005 | |
| 93 | Larry Parker# | 47 | 2024-2031 | |
| 96 | Erick Aybar | 46 | 2007-2018 | |
| 96 | Brian Boyd | 46 | 2003-2013 | |
| 96 | Marc Clark# | 46 | 2024-2031 | |
| 96 | Bill Spiers | 46 | 1989-2002 | |
| 100 | Carl Hastings | 45 | 2012-2016 |
